The instability of the Safari extension is known, and there is even a fix implemented in 1P8 (also production version):
Help => Troubleshooting => Fix Missing Safari Extension
While this is a work around that does help, it is really disappointing that one has to use it that often.
Before the update to Monterey 12.5, I had to use the fix maybe twice a month, now it is almost every day. The loss happens on all my machines (MBP16, iMac24, MBP15-Intel), again and again.
Just an additional note: this did never happen with 1P7 ... there is a LONG (!!) way to go until 1P8 reaches the quality of the former versions (note the plural)! If I would not be a 1P user since the beginning, I would NOT use 1P8 but start with alternative solutions.
1Password Version: 80900001 BETA
Extension Version: 2.3.7
OS Version: 12.5