Yesterday I updated the Safari extension and today 1P is not working in Safari. By that I mean that when I have a sign-in window to fill, "Unlock 1Password" does nothing. Looking here for what to do, I discovered that I should "Look for our helper in the menu bar near the WiFi indicator and the clock. Right-click (Option-click) on the helper and select quit 1Password completely" -- but I can't do that because there is no 1P icon in the menu bar.
Yesterday, I had a different problem, on my iPad version. The solution (described elsewhere in this forum) was to delete the "Primary" vault on the iPad, so that only the "Personal" vault was left. I realize it shouldn't have been that way. My MacAir (which I'm writing from), my Mini (at the office), my iPhone, and now the iPad only have the Personal vault.
Version 7.8.6 (70806000)
Mac App Store